Egyptian Mummies Diagnosed With Clogged Arteries

The mummy Maiherpri undergoes CT scanning. Study results call into question the perception of atherosclerosis as a modern disease.

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LINDA WERTHEIMER, host: Seventeen million people died of cardiovascular diseases(心血管疾病) last year alone, and that number is only expected to rise. Heart disease is supposed to be the result of the good living that modern life affords us, a diet rich in animal fat, too many hours spent on the sofa. But recent discoveries suggest that strokes and heart attacks may not just be the scourge(灾祸) of modern society.

Joining us to explain is Dr. Greg Thomas. He is coauthor of a paper in the Journal of the American College of Cardiology(心脏病学) Imaging that describes a heart disease among ancient Egyptians, specifically mummies.

Dr. Thomas, welcome.

Dr. GREG THOMAS: Thank you.

WERTHEIMER: Now, everything that I know about mummies, I learned in the National Geographic. But as I recall, mummies had all their innards(内脏) emptied out and stored in canopic jars(卡诺皮克罐). So how did you do your research?

Dr. THOMAS: Well, it turns out there's not a canopic jar for the heart. They're for the abdominal(腹部的) organs. And so...

WERTHEIMER: I see.

Dr. THOMAS: ...predominantly, the heart was still there.

WERTHEIMER: And so what did you do?

Dr. THOMAS: We did CT scanning at a scanner that had been donated actually by National Geographic - your teacher - to the Cairo Museum, their national museum, and imaged 52 mummies who had been in their museum. And to our surprise  we found they did have vascular(血管的) disease, atherosclerosis(动脉硬化), in many of their large arteries, and the small arteries of the body that cause events, for example, the arteries in the heart and the arteries to the brain, also had atherosclerosis.

WERTHEIMER: Now, that's a sign of a calcification(钙化,石灰化).

Dr. THOMAS: Right. When we develop atherosclerosis or plaque(血小板) or harden the arteries, it starts with cholesterol(胆固醇) and other cells. And then as it ages, it calcifies, so it kind of ossifies(骨化) like a bone. So our hypothesis was that the calcium might still be there 3,000 years later to see if they indeed had these blockages(阻塞,封堵).

WERTHEIMER: So you had a lot of mummies to pick from, presumably. How'd you choose them?

Dr. THOMAS: We looked for older mummies. We found, for example, a general. We thought, well, it took some time to be a general. He must be old. And so they were able, actually, to unscrew(旋开) the glass case and look down the sarcophagus(大理石棺) and see someone been there for 3,000 years and then take him out of the sarcophagus and bring him over to scan. And I was just, you know, pinching myself to see how fortunate I was to look inside with a CT scanner and see what was going on.

WERTHEIMER: One of the mummies that you scanned was a princess who had severe atherosclerosis. Now, presumably, this woman was a locavore(土食者), ate fresh things -there was no refrigeration. She would not have been sedentary(久坐的) because she would have had no elevators. I mean, why would she get this kind of thing?

Dr. THOMAS: Well, our hypothesis is they wouldn't have them because they were active, their diet was much different, they didn't have tobacco. But to our surprise, they had atherosclerosis in the large arteries, as well as the small arteries that can cause problems. For example, in this woman who died 1550 B.C. approximately in her 40s, that she would have atherosclerosis, I think we're missing a risk factor(风险因素).

Right now, we know that high blood pressure, smoking, cholesterol, inactivity and other things caused atherosclerosis, but I think that we're less complete than we think.

WERTHEIMER: Now, obviously, working people did not merit mummification(木乃伊化). Do you think that your research might be showing us a very inbred(近亲交配) group, these aristocrats(贵族)?

Dr. THOMAS: Well, the pharaohs(法老) and their families did like to keep the power and the wealth. So they would often, brothers and sisters, would be married. But we found the atherosclerosis over 2,000 years of time, and so there would be many different families who were the pharaohs or the ruling parties at the time. So it was - we think it's common to the environment there among the people who were the elite(中坚分子).

So they did have access to meat. They actually had domesticated cattle, goats, antelope, gazelles(瞪羚) and pigs. However, we think that predominantly, their diet was grains, fruits and vegetables and not near as much meat. We do hope in future expeditions to find mummies of the more common class, but we're suspicious that even the more middle class persons, that they may well have had it, but that's research to be done.

WERTHEIMER: That's Dr. Gregory Thomas, a member of the team that discovered heart disease in Egyptian mummies.

Dr. Thomas, thank you.

Dr. THOMAS: You're welcome.

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