沪江娱乐:北京时间4月26日,据报道,杜汶泽前天被医生诊断患上极罕有病症米勒费雪症候群,严重者会四肢瘫痪、窒息致死!由于患上该病,杜汶泽需急停所有工作留家养病,单单两个月已不见七位数酬劳!

香港近月天气乍暖还寒,不少市民中招患感冒,杜汶泽也不例外。病了近一个月后,他日前突然看物件时出现重影,四肢肌腱反射消失,更出现平衡失调情况,经医生仔细诊症后,发现他患上罕有病症“米勒费雪症候群”(Miller Fisher)。据知,严重病患者会出现四肢瘫痪,甚至呼吸困难,窒息致死。

杜汶泽昨天接受电话访问时谈及现在病况,他说:“因为我住独立屋,现在上下楼梯会好小心,由于香港很少出现这个病,所以医生将我的血送去美国化验,看下严重程度,康复时间应该是两个星期至半年不等。”现在看东西重影、四肢麻痹的杜汶泽,仍乐观表示:“虽然这个病严重的话会致命,但很少会去到这个情况!”

杜太田蕊妮在25日晚21:40发微博力挺丈夫,“当你病时,不能在你的身边照顾你,还反过来要你安慰我!佩服当你遇到逆境时还能如此安然松坦的去面对!在你身上,我学习到狠多!你是我心目中的巨人!”

【关键词】米勒费雪症候群(Miller Fisher症候群)

What is Miller Fisher Syndrome? 米勒费雪症候群是什么?

Miller Fisher syndrome is a rare, acquired nerve disease that is considered to be a variant of Guillain-Barré syndrome. It is characterized by abnormal muscle coordination, paralysis of the eye muscles, and absence of the tendon reflexes. Like Guillain-Barré syndrome, symptoms may be preceded by a viral illness. Additional symptoms include generalized muscle weakness and respiratory failure. The majority of individuals with Miller Fisher syndrome have a unique antibody that characterizes the disorder.

Is there any treatment? 有治疗办法吗?

Treatment for Miller Fisher syndrome is identical to treatment for Guillain-Barré syndrome: intravenous immunoglobulin (IVIg) or plasmapheresis (a procedure in which antibodies are removed from the blood) and supportive care.

What is the prognosis? 有什么预兆?

The prognosis for most individuals with Miller Fisher syndrome is good. In most cases, recovery begins within 2 to 4 weeks of the onset of symptoms, and may be almost complete within 6 months. Some individuals are left with residual deficits. Relapses may occur rarely (in less than 3 percent of cases).

What research is being done? 医学界对此病有何研究?

The NINDS supports research aimed at discovering new ways to diagnose, treat, and, ultimately, cure neuropathies such as Miller Fisher syndrome. 

米勒费雪症候群(Miller Fisher症候群) 是一种罕见的、后天的多发性神经炎疾病,被认为是格林-巴利综合征的变体。其病因目前仍不甚明暸。其病理现象即为脑干之脑神经核体功能缺损。一旦上脑神经核体功能异常,则患者会有眼球运动麻痹或运动失调等现象,若下脑神经核体受损,则会有吞咽功能之异常。依据过去的报告约有 40% Miller Fisher症候群患者于生病期间有吞咽障碍之产生,但这些报告对吞咽障碍之治疗及预后,少有提及。

米勒费雪症候群(Miller Fisher syndrome)及毕氏脑干脑炎(Bickerstaff brainstem encephalitis)都属于Guillian-Barre症候群的鉴别诊断之一。是一种常见在感染后发生的神经根发炎及脑干发炎的疾病。相较于米勒费雪症候群,毕氏脑炎较为少见且较为严重。两者都会出现运动失调(ataxia),眼外肌麻痹(ophthalmoplegia)等症状。由于影响到脑干,毕氏脑炎患者可能会出现意识障碍(impaired consciousness)或反射增强(hyper-reflexia)的现象。米勒费雪症候群及毕氏脑炎的病患,大多于发病前一周会出现前驱的感染症状,且以上呼吸道感染为主。空肠弧菌(Campylobactar jejuni)是常见的相关感染病菌之一。致病机转可能为患者体内出现对抗空肠弧菌外膜(outer membrane)的脂-寡醣(Lipo-oligosaccharide)的抗体,进而攻击兰氏节(Nodes of Ranvier)及神经肌肉交界(neuromuscular junction)的神经节脂(gangliosides)所导致。