众叛亲离的英文：
[Literal Meaning]
mass/rebel against/relative/leave
to be opposed by the masses and deserted by one's relatives

[解释]
人们都背叛、远离，感到完全孤立。

[Explanation]
be utterly isolated

[例子]
因为暴躁的性格，他的家人也都离开他了，真是到了众叛亲离的地步。

[Example]
For his irritable character, his families all left him, he was utterly isolated.

参考例句：
  • be deserted by one's followers;Opposed by the masses and deserted by one's followers
    众叛亲离

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