Meredith Grey (Ellen Pompeo) is about to lose her person for good.

"Grey's Anatomy" star Sandra Oh is leaving the ABC hit medical drama, The Hollywood Reporter reports. Oh -- who has played original cast member doctor Cristina Yang since the series premiered in 2005 -- will leave the series after the upcoming Season 10 ends.

"Creatively, I really feel like I gave it my all, and I feel ready to let her go," Oh says. "It's such an interesting thing to play a character for so long and to actually get the sense that she wants to be let go as well. [Cristina] wants to be let go, and I am ready to let her go. We have to start the process, story-wise, for the 'Grey's' writers to think of why she's going to go."

There is no word yet on how Oh's departure will translate onscreen. And while at this time no additional cast members are expected to follow her lead and leave the series, the two-year contracts for stars Pompeo, Patrick Dempsey (Derek), Justin Chambers (Alex), James Pickens Jr. (Webber), and Chandra Wilson (Bailey) are all up at the end of season 10 so who know what will happen between then and now. In the meantime, the four interns have been promoted to series regulars.

"Grey's Anatomy" Season 10 premieres on Sept. 26 on ABC. 


《实习医生格蕾》中 Meredith 的好姐妹,由吴珊卓饰演的 Cristina Yang 将在第十季之后离开剧组。吴珊卓说:“我已经将我的全部给了这个角色,我准备好放开她了。这么长时间出演同一个角色是一件有趣的事儿,现在我已经为这个角色的离开做好了准备。” 对于 Cristina 这个角色在剧中将如何离开,我们并不知道。目前,剧组并没有其他演员要步吴珊卓后尘,他们的合约都是两年的,到第十季结束。《实习医生格蕾》第十季将于9月26日在 ABC 电视台首播。