科学60秒:饮食基因与变异基因大作战
People with the genetic variant 9p21 have an increased risk for heart disease—one of the most common killers worldwide.
Researchers collected genetic and dietary information from more than 8,000 people of various ethnicities, as well as data from 20,000 Finish subjects. People who had the genetic variant, but who ate a diet rich in fruits, raw vegetables and nuts, ended up on average with a heart attack risk close to people who don't have this genetic ___3___. While those with the trait who did not follow such a ___4___ diet had as much as twice the chance of having a heart attack. [Ron Do et al., "The Effect of Chromosome 9p21 Variants on Cardiovascular Disease May Be Modified by Dietary Intake: Evidence from a Case/Control and a Prospective Study," in Public Library of Science Medicine, link to come]
So a healthful diet might actually be changing the expression of the gene, in effect turning it off. Which suggests that there might be more diet-gene ___5___ than you can shake a carrot stick at.
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