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Today, diabetics monitoring their blood sugar sometimes have to endure multiple needle pricks every day. But biomedical engineer Heather Clark of Draper Laboratory is developing a less invasive way to measure blood glucose. She describes it as a "nanotech tattoo".

Heather Clark: [---1---]

[---2---] The dye would be made of nanoparticles — microscopic molecules of plastic that would actually change color.

Heather Clark: [---3---] And so you can monitor either by color or by fluorescence.

[---4---]

Heather Clark: Some sort of optical device no more complicated than the optical mouse on your computer…

Clark added that the tattoo would have to be periodically re-injected, because it would shed along with the skin. [---5---]

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What we envision is something very, very small, on the order of a few millimeters, which would be thousands or millions of nanoparticles, certainly. As with an ordinary tattoo, Clark said, dye would be injected beneath the skin of someone with diabetes, but this tattoo would require only one tiny pinprick. And so when the glucose is low, the particle is yellow and it's fluorescent, and when the glucose is high, the particle is purple, and the fluorescence goes away. She said diabetics would have to shine a little light on the tattoo to help get a more accurate read on its glow. She hopes to see this technology up and running in five to ten years.