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A new development in malaria:

疟疾的最新研究进展:

Plasmodium vivax, the world’s most common malaria parasite, now infects people previously considered to be resistant.”

“间日疟原虫是世上最常见的疟疾寄生虫,现在,这种寄生虫也会感染那些之前被认为抗疟疾病的人。”

Peter Zimmerman from Case Western Reserve University school of medicine spoke at the AAAS meeting in Washington on February 19th.

在2月19日,来自凯斯西储大学医学院的皮特·齐默曼于华盛顿在美国科学发展协会会议中发表讲话。

“So, red blood cells of most African people do not express the Duffy blood-group protein. Now, the Duffy blood-group protein is essentially necessary for Plasmodium vivax to get into the red cell. Duffy-negative Africans have been considered to be resistant to Plasmodium vivax.”

“因此,大部分非洲人的红细胞不会表达达菲蛋白。现在间日疟原虫必须依靠达菲蛋白进入红细胞。不表达达菲蛋白的非洲人曾被认为是不会感染间日疟原虫的。”

Zimmerman studied Malagasy populations on Madagascar. He found that 10 percent of Duffy-negative subjects were in fact infected with Plasmodium vivax.

齐默曼研究了马达加斯加上土地上的马达加斯加人。他发现10%没有达菲蛋白的人实际上都被间日疟原虫感染了。

Peter Zimmerman from Case Western Reserve University school of medicine spoke at the AAAS meeting in Washington on February 19th.

在2月19日,来自凯斯西储大学医学院的皮特·齐默曼于华盛顿在美国科学发展协会会议中发表讲话。

“So we’ve shown that Plasmodium vivax has cleared Duffy negativity. If Plasmodium vivax is evolving to learn how to infect the Duffy-negative red cell, then a large continent of people suddenly becomes susceptible to a new form of malaria.”

因此我们证明了不表达达菲蛋白的人已经不再能抵抗间日疟原虫了。如果间日疟原虫进化到可以影响不表达达菲蛋白的红细胞,那么突然之间,这片大陆上就会有很多人可能患上了一种新的虐疾病。

—Steve Mirsky

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